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October 2024

link between hypothyroidism and bipolar disorder
Scientific Perspectives

Is There a Link Between Hypothyroidism and Bipolar Disorder?

Is There a Link Between Hypothyroidism and Bipolar Disorder? Bipolar disorder is a complex mental health condition distinguished by extreme mood shifts. Hypothyroidism is a state in which a person suffers from abnormally low thyroid gland activity, resulting in metabolic changes in adults. The symptoms between these two illnesses are remarkably similar, which leads to misdiagnoses and improper treatment.  Our holistic approach to mental health encourages us to consider how underlying physical conditions, like hypothyroidism, might impact mental health disorders. By understanding how hypothyroidism can exacerbate or even mimic symptoms of bipolar disorder, we gain new insights into the importance of a whole-body approach to managing mental health. Understanding the Connection Between the Thyroid and Mental Health The thyroid gland, located at the base of the neck, produces hormones that regulate energy, metabolism, and mood. The body’s ability to regulate these essential functions diminishes when the thyroid is not performing sufficiently, as in hypothyroidism. Common symptoms of hypothyroidism include fatigue, depression, memory problems, weight gain, and slowed cognitive function.   Thyroid dysfunction can directly impact mental health by disrupting neurotransmitter balance, affecting mood stability and cognition. Since neurotransmitters are essential for mood regulation, an underperforming thyroid can lead to symptoms that overlap significantly with mood disorders like bipolar disorder. This overlap can often result in misdiagnoses, where individuals with hypothyroidism might be diagnosed with bipolar disorder when, in reality, addressing their thyroid dysfunction could alleviate their mental health symptoms. In the case that hypothyroidism is a comorbidity, addressing the thyroid gland can significantly lower bipolar symptoms. Symptoms Overlap Between Hypothyroidism and Bipolar Disorder There is a significant overlap in symptoms between hypothyroidism and bipolar disorder, particularly in the depressive phase. Many symptoms of hypothyroidism—such as fatigue, irritability, cognitive slowing, and depression—can also be present in bipolar disorder.This overlap can be particularly challenging when it comes to diagnosis. For instance, during a depressive phase, a person with bipolar disorder may experience severe fatigue, weight changes, and low mood—all of which are also common in hypothyroidism. Conversely, untreated or undiagnosed hypothyroidism may cause mental health symptoms that are wrongly attributed to bipolar disorder, leading to treatment that addresses symptoms without tackling the underlying cause. Unfortunately, in cases where hypothyroidism is undiagnosed, individuals might receive mood stabilizers or antidepressants, which can be ineffective or even counterproductive if thyroid issues remain unaddressed.  Hypothyroidism’s Impact on Neurotransmitters and Mood One key area of research in modern psychiatry is the role of neurotransmitters, such as serotonin, dopamine, oxytocin, and norepinephrine, in mood regulation. Hypothyroidism affects the brain’s ability to produce and regulate these neurotransmitters, leading to emotional instability and cognitive difficulties, which may present as symptoms similar to bipolar disorder.  Low thyroid hormone levels can cause a reduction in dopamine, the neurotransmitter that contributes to feelings of motivation and pleasure. This decrease in dopamine can result in anhedonia — a loss of interest in enjoyable activities—, low motivation, and feelings of hopelessness. Meanwhile, low serotonin levels, often seen in hypothyroidism, contribute to depression and anxiety. This hormonal imbalance can create the emotional rollercoaster that individuals with bipolar disorder frequently experience.  A Holistic Path to Healing In conventional medicine today, endocrinologists will administer medication and supplements like selenium for individuals with hypothyroidism. At BP Harmony, we are a proponent of integrative, root-cause medicine, advocating for approaches that consider the whole person rather than merely treating symptoms. We argue that conventional treatments often overlook underlying physical causes, like hypothyroidism, that may be contributing to mental health issues.  Hence, we recommend a comprehensive approach for those diagnosed with bipolar disorder that involves screening for thyroid dysfunction alongside other underlying health conditions that might be influencing mental health. Our approach includes working with integrative medicine physicians, making nutritional changes, detoxification, and lifestyle modifications supporting thyroid and mental health.  Nutritional Support for the Thyroid: Diet is one of the foundational elements we emphasize for supporting thyroid health. We suggest minimizing processed foods, refined sugars, and inflammatory substances, which can contribute to hypothyroidism. Instead, a diet rich in whole foods, notably those high in iodine, selenium, and zinc, can support thyroid function. Sea vegetables, seafood, nuts, and whole grains offer nutrients that boost thyroid health, which may positively impact mood stability. Moreover, consider eliminating gluten and dairy, as these two food types are often at the root of thyroid dysfunction. Learn more about the best diet for bipolar disorder here. Detoxification: Toxins such as heavy metals and endocrine disruptors (often found in household chemicals and certain foods) can impair thyroid function. We encourage reducing exposure to these toxins by opting for natural cleaning products, avoiding plastic containers, and choosing organic foods when possible. Detoxification practices such as sweating through exercise or sauna use and consuming antioxidant-rich foods can help the body eliminate these harmful substances. Mindfulness and Stress Reduction: Chronic stress negatively affects both thyroid and mental health, with elevated cortisol levels inhibiting thyroid hormone production. BP Harmony’s approach includes stress-reduction techniques like meditation, yoga, and deep breathing exercises to lower cortisol levels and support thyroid health. By reducing stress, individuals can foster an environment where mental and thyroid health can improve. Addressing Nutritional Deficiencies: Hypothyroidism is sometimes linked to deficiencies in essential nutrients like vitamin D, B12, and iron. The latest medical research from Harvard Medical School and Cleveland Clinic recommends getting tested for deficiencies and supplementing as necessary, as these nutrients play a critical role in thyroid function and neurotransmitter synthesis. Addressing these nutritional needs through food and supplements if they are incredibly deficient can support overall mood stability and energy levels. The Path Forward This blog post begins to shed light on the intricate relationship between hypothyroidism and bipolar disorder. By understanding how thyroid health can influence mood and mental well-being, individuals with bipolar disorder may have the opportunity to address an underlying physical cause of their symptoms, potentially improving mood stability and overall quality of life.If you or someone you know has bipolar disorder and exhibits symptoms of hypothyroidism, it may be worthwhile to explore this connection with a

Scientific Perspectives

Severe Psychosis & Bipolar Disorder – Are They Linked?

Severe Psychosis & Bipolar Disorder – Are They Linked? Living with bipolar disorder often means dealing with extreme mood swings. People with this condition can feel the fast, dizzy excitement of mania and the deep, heavy sadness of depression. In this blog post, we will talk about one serious effect of bipolar disorder: psychosis. When someone has their first manic episode and doesn’t know they have bipolar disorder, they might feel very energetic, super confident, and like nothing can stop them. These feelings can make them sleep very little, believe they are more important than they really are, spend too much money, and act in unusual ways. Staying in this high-energy state can be dangerous. If you add stress, drug or alcohol use, or trauma, the person could develop psychosis. The relationship between bipolar disorder and psychosis makes life even harder for people with this condition. To understand this better, let’s look at the main ways these two experiences connect. For more guidance on bipolar disorder, check out our book and masterclass to reclaim control of your life. You can also check out our free resources.  Panic Amid the Chaos: A First Look at Bipolar Disorder and Psychosis The Oxford Dictionary says psychosis is “a severe mental condition in which thought and emotions are so affected that contact is lost with external reality.” This means that if someone with mania loses touch with what is real, they have reached a psychotic state. For people with bipolar disorder, going back and forth between mania and depression can feel confusing and overwhelming. Now, imagine how much scarier it gets when they also start to lose touch with reality. This is what happens when someone has a manic episode with psychotic features. When a person experiences psychosis, they might feel stuck in a storm of fear and confusion. They can’t always tell the difference between what is real and what is not. Panic often takes over. Some people say they feel chased by thoughts, images, or sounds that aren’t really there. This can cause them to act in ways that are unusual, unpredictable, and sometimes dangerous. Psychosis and Mania When we talk about bipolar disorder, especially in its most serious forms, we are talking about more than just mood swings. Sometimes, mania can become much more severe and include psychotic features. This means someone with mania might not only feel overly happy, irritable, or full of energy, but they could also lose touch with reality. For some people, this means they hear voices or see things that aren’t really there  (hallucinations). Others might have delusions, which are strong beliefs that aren’t true. For example, a person might believe they are the president while sitting in their living room, or think they have been chosen to save the world. These hallucinations and delusions feel completely real to the person, even if others around them are confused or worried. Some people with psychosis believe they see secret messages in lights, colors, numbers, or even videos online. This can make their thoughts and actions feel confusing and out of control, and it can be very hard for them to come back to reality. It’s important to know that bipolar mania with psychotic features is not rare. More than half of people with bipolar disorder will experience psychosis at some point in their lives. Psychosis and Depression Psychosis usually happens more often during manic episodes, but it can also show up during very bad depressive episodes. This means a person with bipolar disorder might go back and forth between deep depression and mania, and sometimes have psychotic symptoms during both. When someone is in a major depressive episode, they might feel extremely hopeless, guilty, or worthless. If psychosis happens at the same time, these feelings can turn into strong false beliefs or seeing and hearing things that make the negative thoughts worse. For example, a person might believe they caused something terrible to happen, or they might hear voices telling them to do something harmful. Sometimes, they may even see or hear memories that are so real, it feels like they are living through the scary event again, which can cause a lot of fear and panic. These strong mood swings and psychotic symptoms can make bipolar disorder very unpredictable and dangerous. It’s not just about feeling really happy or really sad; it’s also about the risk of losing touch with reality during both mania and depression, which makes bipolar disorder much more serious than just a mood problem. Guardrails to Protect Against Psychosis For people living with bipolar disorder, especially when psychosis is involved, it’s very important to manage the condition well. Doctors usually treat bipolar disorder with medication like mood stabilizers (such as lithium or valproate) and antipsychotics. These medicines help control mood swings and psychotic symptoms. Psychotherapy (talk therapy) is also helpful. It teaches people how to spot triggers, handle stress, and develop coping skills for dealing with mania, depression, and psychosis. Family and friends play a big role in helping someone with psychosis. Experts suggest that a person the individual trusts should: Listen carefully and notice if their thoughts don’t match reality. Ask if these thoughts are new or if they’ve always had them. If the thoughts are new, gently point out that things have changed. Show concern and invite the person to think about how their life has changed. Offer support by saying you’ll help them figure things out together, instead of just saying they need help. Telling someone they need help might make them push others away. It can be very hard for someone deep in psychosis to realize they’re not seeing reality. That’s why it’s important for a trusted person, psychiatrist, and therapist to work together. If the person is at risk of hurting themselves or others, it’s safest to get them proper medical care right away—sometimes this means going to the hospital. Conclusion The link between bipolar disorder and psychosis is complex. Not everyone with bipolar disorder will have psychotic symptoms, but for

bipolar vs unipolar depression
Understanding Bipolar Disorder

The Difference Between Bipolar Disorder and Unipolar Depression

The Difference Between Bipolar Disorder and Unipolar Depression Bipolar disorder and unipolar depression share many similarities, but they are fundamentally different in how they affect mood, the approach to treatment, and the role lifestyle plays in managing symptoms. Understanding these differences clarifies and helps people seek the right support. Let’s explore how these two conditions diverge in symptoms, treatment, and the potential for healing through lifestyle changes. Symptoms: Distinguishing the Two Conditions Bipolar and unipolar depression affect mood similarly in some ways and differently in key areas. Recognizing these distinct symptoms can lead to quicker, more accurate diagnoses and effective treatment. As we have discussed in previous posts, bipolar disorder presents itself as extreme fluctuations between emotional highs (mania or hypomania) and lows (depression), varying in frequency and intensity. These mood swings make it far more complex than unipolar depression though we are not discounting the severity and life-threatening nature of depression.  Unipolar Depression, on the other hand, is defined solely by persistent depressive symptoms. Unlike bipolar disorder, it does not involve manic or hypomanic episodes. Depressive episodes in unipolar depression are characterized by deep feelings of sadness, hopelessness, and a lack of energy. Physical symptoms like sleep and appetite changes often accompany these emotional lows. Another common characteristic is anhedonia, or the inability to experience pleasure. Those with unipolar depression may struggle to find joy in activities they once enjoyed, often feeling trapped in a low mood for extended periods like weeks, months, or even years. Treatment: Tailored Approaches for Bipolar And Unipolar Depression The difference between bipolar and unipolar disorder lies in the treatment path too. The focus for bipolar disorder is on stabilizing mood between two extremes, while treatment for unipolar depression centers on lifting the persistent feelings of sadness. Bipolar disorder requires a careful balancing act to manage both mania and depression. You can learn more about various treatment strategies in a previous post, but it is always recommended to work with a licensed health professional to get specific treatment advice. The general medication categories for bipolar disorder are mood stabilizers, antipsychotics, and sometimes antidepressants because of the risk of triggering hypomania or mania.  Unipolar Depression treatment focuses on alleviating depressive symptoms only. The absence of manic episodes means fewer variables to manage that are no less severe and challenging.Antidepressants are commonly prescribed to regulate mood by balancing neurotransmitters in the brain, lifting the cloud of depression. The Power of Lifestyle Changes A common thread and place for communal collaboration between the two patient communities is lifestyle. Lifestyle changes can have a profound impact on both bipolar disorder and unipolar depression. While these conditions may not be “curable,” individuals can achieve a “reversal” to the extent that the symptoms no longer exist.  In summary, bipolar disorder involves the complex interplay between mania and depression, requiring careful monitoring and stabilization. Unipolar depression focuses on lifting individuals from a persistent low mood. At BP Harmony, we have worked with Unipolar Depression clients by modifying the Five Pillars of Bipolar Disorder Recovery model: Sleep, Nutrition, Movement, Mindfulness, and Community. These five pillars are a recipe for good health for anyone, but when catered specially for people dealing with the extreme states of bipolar and unipolar depression, it can offer a significant decrease in suffering and the possibility of living full lives again.

bipolar disorder and spirituality
Understanding Bipolar Disorder

The Link Between Bipolar Disorder and Spirituality

The Link Between Bipolar Disorder and Spirituality   Bipolar disorder (BPD) often feels like a force that pulls life apart. Yet, for those who face this challenge, there’s a possibility for deeper meaning and growth hidden within its chaos. Spirituality—whether through religious faith or personal practice—can offer solace and a framework for understanding this unique experience. It is through this lens that many find hope and insight. This post argues that what is often viewed as suffering can be changed into a meaningful journey. For more guidance on bipolar disorder, check out our book and masterclass to reclaim control of your life. You can also check out our free resources.  Spirituality: A Shelter Amidst the Storm Spirituality is more than just a set of beliefs or practices. It can be the ground beneath your feet when the world feels unsteady. Mental illness, particularly bipolar disorder, presents many trials, and spirituality can infuse these challenges with meaning.  BPH’s founder grew up as a Muslim. His faith gave him strength and comfort. Daily prayers and rituals helped him feel calm and safe, like someone loving was always listening. Some people see God as a power outside themselves. Others see God as a voice inside. Either way, faith can help people feel steady. Even religions like Buddhism, which don’t focus on a god, teach deep thinking and mindfulness. The spiritual road begins by asking critical questions: Why is this happening? What does this moment seek to teach me? In facing mental illness, these questions can illuminate a path forward. The purpose of this struggle may not be immediately clear. But, through reflection, it often becomes possible to transform pain into understanding. Trial as Purification Life’s trials have a way of shaping us, and few trials are as intense as navigating bipolar disorder. However, in many spiritual traditions, there’s a belief that trials are not random—they serve as opportunities for purification. In Islam, hardship is seen as a test of character, a way to cleanse the soul and reconsider one’s choices. It’s a process of refinement, much like gold being purified by fire. The suffering brought on by bipolar disorder can be viewed through this lens. Bipolar burns away what no longer serves us. When health falters, it forces us to reevaluate the mundane and appreciate moments of peace we may take for granted. Spirituality reminds us that this world, with all its suffering and joys, is temporary. Both the highs and the lows are fleeting, but the lessons learned from them are enduring. When one reflects on their journey, there is an opportunity to see how the turmoil can lead to a deeper appreciation of life. It is this perspective, gained through a spiritual framework, that transforms suffering into a process of refinement. Trial as Expansion Beyond purification, mental illness can also expand our capacity for empathy and compassion. You can’t help but feel a closer connection to the suffering of others after your own trials. The moments of despair and elation widen the emotional bandwidth. Thus, it creates space to understand the pain of those around us more profoundly. There is a TED Talk by Phil Borges that challenges listeners to think about mental illness differently. In his research, Borges spoke to shamans from different cultures—people who operate temporarily in heightened states of consciousness. So many of these shamans first realized their calling through experiences we in the West would label as “mental illness.” These shamans, guided by elders, learned to ground their heightened awareness and use it in service to their communities. Borges asked a powerful question, “Are we, in the West, misdiagnosing people who are experiencing spiritual awakenings as mentally ill?” This reframing presents an empowering alternative to the narrative of bipolar disorder as an unchangeable affliction.  What if, instead of merely managing symptoms, we could recognize the potential for awakening that this condition brings? The suffering that once seemed so isolating can become a bridge to an expanded understanding and awareness. The perspective shift from BP as a disability to a potential awakening will take much advocacy, medical research, and courage. People like Phil Borges need the backing of medical experts to create a shift in perspective. At BP Harmony, we believe that this diagnosis can be viewed the way Phil Borges presents.  Trial as Inspiration Mental illness has long been linked with creativity. Bipolar disorder, in particular, is known for inspiring great works of art, music, and literature. The emotional extremes of the condition allow individuals to access depths of feeling that others do not. This wellspring of emotion often finds an outlet in creative expression. Vincent Van Gogh, for example, is one of the most famous artists whose work was deeply intertwined with his struggles with bipolar disorder. His paintings capture an intensity of emotion that resonates on a universal level. In the modern era, artists like Mariah Carey, Kanye West, and Demi Lovato have similarly channeled their own experiences of bipolar disorder into their art. They offer the world a window into the depths of human experience. For this author, poetry became a lifeline during the healing journey. Writing helped make sense of the chaotic emotions. It became a way to transform the turmoil into something beautiful and meaningful. Through creativity, struggle was no longer just as a burden, but as a source of inspiration—a reminder that from suffering, something new and powerful can emerge. Conclusion Bipolar disorder is a profound and often difficult experience, but spirituality can offer a way to reframe it. Whether viewed as a path of purification, expansion, or inspiration, the link between bipolar disorder and spirituality is a powerful one. It allows us to find meaning where there might otherwise be only pain, and to see trials as opportunities for growth and transformation. When we engage with our mental illness from a spiritual perspective, we unlock the potential to transform suffering into something deeper—a tool for self-understanding, compassion, and creative expression. It’s in this alchemy of experience where the true power of spirituality lies: not

right medication for bipolar
Understanding Bipolar Disorder

Selecting the Right Medication for Bipolar Disorder

Selecting the Right Medication for Bipolar Disorder Managing bipolar disorder (BPD) is no easy journey and in many cases requires the use of pharmaceutical medication to minimize the intense symptoms and actions to protect the individual from harm to themselves and others. Because a person typically starts medication during an intense period of mania or depression, decisions are made quickly without properly understanding the benefits and potential risks of taking on medication. Typically, psychiatrists will prescribe bipolar disorder medication based on the symptoms presented, their medical training, and experience. There is a stage in the beginning where they will prescribe medication and observe how the patient reacts. If it works, then they will keep you on the medication and dosage. If it does not help the patient stabilize, then they will adjust the dosage or try a different drug or even drug type. This process of determining the right “cocktail” of drugs to stabilize the individual yields strong side effects and is designed to lessen or completely mute symptoms. They do not, however, cure the root cause, which is a combination of genetic components and external factors like stress, trauma, and lifestyle choices. In this post, we’ll explore the various classes of medications used to manage bipolar disorder, examples of commonly prescribed drugs, potential side effects, and the crucial role of lifestyle changes. When medications are combined with practices like sleep hygiene, movement, mindfulness, and community support, one begins the process of healing and potentially liberating oneself from medication partially if not completely. Types of Bipolar Disorder Medication Mood Stabilizers If you have bipolar disorder, mood stabilizers will likely be at the core of your medication treatment. These medications help to keep the extremes of mood in check, reducing both manic and depressive episodes by primarily affecting neurotransmitters and receptors. Let’s discuss some of the most commonly prescribed mood stabilizers in the US. Lithium: This is a strong medication for bipolar treatment, especially for mania. Lithium requires close monitoring by a psychiatrist because it can affect kidney and thyroid function. It is effective, yes, but it’s also a commitment. Side effects include weight gain, tremors, frequent urination, and long-term concerns with kidney function. Valproate (aka Depakote): Valproate is another go-to mood stabilizer, especially when lithium is not effective. It’s particularly effective in treating manic episodes. Side effects include weight gain, liver issues, drowsiness, and hair thinning. Regular liver function tests are necessary. While these medications can be lifesavers, they have strong side effects that can be unpleasant to bear. It’s important to openly communicate with your doctor about any side effects you experience so that adjustments can be made in a timely fashion. Anticonvulsants Anticonvulsants were originally developed to treat epilepsy but have proven effective in stabilizing mood, particularly for bipolar depression. Commonly prescribed medications for this class include: Lamotrigine (aka Lamictal): Particularly helpful in preventing depressive episodes, lamotrigine is favored by many because it has fewer side effects compared to other medications and is not as addictive as other medications listed on this blog. Side effects include poor concentration, weak memory, poor coordination, anxiety Carbamazepine (aka Tegretol): This anticonvulsant is primarily used to manage mania and is an option when other treatments fail. Side effects include dizziness, drowsiness, and potential impact on liver function. By now, it is apparent that these medications address mere symptoms and the side effects pose serious challenges for daily life. Presenting patients with only two options of uncontrolled mania/depression or being severely medicated is not a pleasant experience. We will get to a third more empowering option after discussing antipsychotics. Antipsychotics Antipsychotics are also commonly prescribed for acute manic or mixed episodes. From an experiential perspective, they slow down racing thoughts, facilitate falling asleep, and lower severe anxiety. They also serve as maintenance therapy, particularly if mood stabilizers alone aren’t enough. A few include Risperidone (aka Risperdal): this antipsychotic is prescribed particularly during manic or mixed episodes. It helps reduce symptoms like agitation, irritability, and rapid thoughts by balancing dopamine and serotonin levels in the brain. Common side effects include weight gain, sedation, constipation, and dizziness, while serious risks may include tardive dyskinesia and metabolic changes.  Olanzapine (aka Zyprexa): Often used during manic episodes, this medication is highly potent for sleep and is also notorious for significant weight gain and metabolic issues.Side effects include weight gain, increased blood sugar levels, and severe drowsiness. Quetiapine (aka Seroquel): This medication is increasingly popular and effective for both mania and depression. It is also a powerful sedative. Side effects also include weight gain and increased risk of metabolic syndrome. Aripiprazole (aka Abilify): This medication is known for having fewer side effects than other antipsychotics as it is a lighter option for mania or mixed episodes. Side effects include restlessness, weight gain, and sleep disturbances. Antidepressants Depressive episodes in bipolar disorder are tricky because they can tip the patient over to hypomania and even mania, especially if they are used without mood stabilizers. We publish a more nuanced conversation about BPD and antidepressants in future blog posts.  A Warning Before Starting Medication Every medication comes with unpleasant side effects, but what works wonders for one person might not for another. The journey toward finding the right medication will likely include some trial and error, which is also an unpleasant experience. But this experimentation process comes with two major risks: (1) these medications are habit forming and are difficult to abandon and (2) psychiatrists in the US are trained on which medications to prescribe based on a cluster of symptoms, but today (2024) they receive little to know training on how to safely get a patient off! There is little guidance on properly tapering off since going cold turkey runs a high risk of severe withdrawal symptoms and the relapsing into mania or depression. This is why it is vital to work with a healthcare provider who studies your health holistically. A good doctor will ask about lifestyle choices like diet, exercise, sleep, stress, and relationship quality before

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