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October 2024

link between hypothyroidism and bipolar disorder
Scientific Perspectives

Is There a Link Between Hypothyroidism and Bipolar Disorder?

Is There a Link Between Hypothyroidism and Bipolar Disorder? Bipolar disorder is a complex mental health condition distinguished by extreme mood shifts. Hypothyroidism is a state in which a person suffers from abnormally low thyroid gland activity, resulting in metabolic changes in adults. The symptoms between these two illnesses are remarkably similar, which leads to misdiagnoses and improper treatment.  Our holistic approach to mental health encourages us to consider how underlying physical conditions, like hypothyroidism, might impact mental health disorders. By understanding how hypothyroidism can exacerbate or even mimic symptoms of bipolar disorder, we gain new insights into the importance of a whole-body approach to managing mental health. Understanding the Connection Between the Thyroid and Mental Health The thyroid gland, located at the base of the neck, produces hormones that regulate energy, metabolism, and mood. The body’s ability to regulate these essential functions diminishes when the thyroid is not performing sufficiently, as in hypothyroidism. Common symptoms of hypothyroidism include fatigue, depression, memory problems, weight gain, and slowed cognitive function.   Thyroid dysfunction can directly impact mental health by disrupting neurotransmitter balance, affecting mood stability and cognition. Since neurotransmitters are essential for mood regulation, an underperforming thyroid can lead to symptoms that overlap significantly with mood disorders like bipolar disorder. This overlap can often result in misdiagnoses, where individuals with hypothyroidism might be diagnosed with bipolar disorder when, in reality, addressing their thyroid dysfunction could alleviate their mental health symptoms. In the case that hypothyroidism is a comorbidity, addressing the thyroid gland can significantly lower bipolar symptoms. Symptoms Overlap Between Hypothyroidism and Bipolar Disorder There is a significant overlap in symptoms between hypothyroidism and bipolar disorder, particularly in the depressive phase. Many symptoms of hypothyroidism—such as fatigue, irritability, cognitive slowing, and depression—can also be present in bipolar disorder.This overlap can be particularly challenging when it comes to diagnosis. For instance, during a depressive phase, a person with bipolar disorder may experience severe fatigue, weight changes, and low mood—all of which are also common in hypothyroidism. Conversely, untreated or undiagnosed hypothyroidism may cause mental health symptoms that are wrongly attributed to bipolar disorder, leading to treatment that addresses symptoms without tackling the underlying cause. Unfortunately, in cases where hypothyroidism is undiagnosed, individuals might receive mood stabilizers or antidepressants, which can be ineffective or even counterproductive if thyroid issues remain unaddressed.  Hypothyroidism’s Impact on Neurotransmitters and Mood One key area of research in modern psychiatry is the role of neurotransmitters, such as serotonin, dopamine, oxytocin, and norepinephrine, in mood regulation. Hypothyroidism affects the brain’s ability to produce and regulate these neurotransmitters, leading to emotional instability and cognitive difficulties, which may present as symptoms similar to bipolar disorder.  Low thyroid hormone levels can cause a reduction in dopamine, the neurotransmitter that contributes to feelings of motivation and pleasure. This decrease in dopamine can result in anhedonia — a loss of interest in enjoyable activities—, low motivation, and feelings of hopelessness. Meanwhile, low serotonin levels, often seen in hypothyroidism, contribute to depression and anxiety. This hormonal imbalance can create the emotional rollercoaster that individuals with bipolar disorder frequently experience.  A Holistic Path to Healing In conventional medicine today, endocrinologists will administer medication and supplements like selenium for individuals with hypothyroidism. At BP Harmony, we are a proponent of integrative, root-cause medicine, advocating for approaches that consider the whole person rather than merely treating symptoms. We argue that conventional treatments often overlook underlying physical causes, like hypothyroidism, that may be contributing to mental health issues.  Hence, we recommend a comprehensive approach for those diagnosed with bipolar disorder that involves screening for thyroid dysfunction alongside other underlying health conditions that might be influencing mental health. Our approach includes working with integrative medicine physicians, making nutritional changes, detoxification, and lifestyle modifications supporting thyroid and mental health.  Nutritional Support for the Thyroid: Diet is one of the foundational elements we emphasize for supporting thyroid health. We suggest minimizing processed foods, refined sugars, and inflammatory substances, which can contribute to hypothyroidism. Instead, a diet rich in whole foods, notably those high in iodine, selenium, and zinc, can support thyroid function. Sea vegetables, seafood, nuts, and whole grains offer nutrients that boost thyroid health, which may positively impact mood stability. Moreover, consider eliminating gluten and dairy, as these two food types are often at the root of thyroid dysfunction. Learn more about the best diet for bipolar disorder here. Detoxification: Toxins such as heavy metals and endocrine disruptors (often found in household chemicals and certain foods) can impair thyroid function. We encourage reducing exposure to these toxins by opting for natural cleaning products, avoiding plastic containers, and choosing organic foods when possible. Detoxification practices such as sweating through exercise or sauna use and consuming antioxidant-rich foods can help the body eliminate these harmful substances. Mindfulness and Stress Reduction: Chronic stress negatively affects both thyroid and mental health, with elevated cortisol levels inhibiting thyroid hormone production. BP Harmony’s approach includes stress-reduction techniques like meditation, yoga, and deep breathing exercises to lower cortisol levels and support thyroid health. By reducing stress, individuals can foster an environment where mental and thyroid health can improve. Addressing Nutritional Deficiencies: Hypothyroidism is sometimes linked to deficiencies in essential nutrients like vitamin D, B12, and iron. The latest medical research from Harvard Medical School and Cleveland Clinic recommends getting tested for deficiencies and supplementing as necessary, as these nutrients play a critical role in thyroid function and neurotransmitter synthesis. Addressing these nutritional needs through food and supplements if they are incredibly deficient can support overall mood stability and energy levels. The Path Forward This blog post begins to shed light on the intricate relationship between hypothyroidism and bipolar disorder. By understanding how thyroid health can influence mood and mental well-being, individuals with bipolar disorder may have the opportunity to address an underlying physical cause of their symptoms, potentially improving mood stability and overall quality of life.If you or someone you know has bipolar disorder and exhibits symptoms of hypothyroidism, it may be worthwhile to explore this connection with a

Scientific Perspectives

Severe Psychosis & Bipolar Disorder – Are They Linked?

Severe Psychosis & Bipolar Disorder – Are They Linked? The experience of bipolar disorder can be summarized by the vacillating, dizzying highs of mania and the crushing, murky lows of depression. The focus of this blog post is to highlight an extreme byproduct of bipolar disorder: psychosis.  Someone who experiences mania for the first time without a diagnosis or any prior history might think they are extra productive, super confident, and utterly invincible. These feelings lead to little to no sleep, thoughts of grandeur, excessive spending possibly, and more irregular behaviors. The dangers of staying in this heightened state are many, but when mixed with things like stress, substance abuse, and trauma, a person can tip over into psychosis. This complex dynamic between bipolar disorder and psychosis can make an already difficult condition even more challenging to navigate. To understand this connection, let’s explore the key elements linking these experiences. Panic Amid the Chaos: A First Look at Bipolar Disorder and Psychosis The Oxford Dictionary defines psychosis as, “a severe mental condition in which thought and emotions are so affected that contact is lost with external reality.” It is this loss of contact with reality that tells if a person experiencing mania has also reached a clinically psychotic state.  For anyone dealing with bipolar disorder, the cycle between mania and depression is disorienting. Imagine, then, the added confusion when panic sets in—not just from the swings themselves but from losing touch with reality. This is what happens when bipolar disorder manic episodes are paired with psychotic features. A person experiencing psychosis may find themselves trapped in a whirlpool of fear and misunderstanding, where they cannot differentiate between what is real and what is imagined. Panic becomes the overriding emotion. People often describe feeling chased by thoughts, images, or sounds that aren’t there, leading to behaviors that are out of character, unpredictable, and often harmful. Psychosis and Mania When we talk about bipolar disorder, especially in its most extreme forms, we’re not just talking about mood swings. In some cases, mania can evolve into something far more severe—bipolar mania with psychotic features. This type of mania doesn’t just involve elation, irritability, or hyperactivity; it can also include episodes of psychosis, where, as mentioned above, individuals lose touch with reality. For some, it means hearing voices or seeing things that aren’t there. For others, it involves delusions—firmly held false beliefs. Imagine believing you are the president of a country, when in fact you are sitting in your living room. Or perhaps you think you’ve been chosen by a higher power to save the world. These delusions and hallucinations are entirely real to the person experiencing them, even though those around them may be baffled by what’s happening. Witness accounts recount how clinically psychotic people believe cryptic messages are coming from the government in the forms of lights, colors, numbers, and even recorded videos on the internet. One can only imagine the chaotic rabbit hole a person experiencing psychosis may go down and find it difficult to come back. What’s important to recognize is that bipolar mania with psychotic features is not uncommon. It’s a significant symptom for many individuals living with bipolar disorder.  Psychosis and Depression While psychosis occurs more commonly with manic episodes, it sometimes occurs during severe depressive episodes. In other words, an individual might cycle between major depressive episodes and manic episodes, sometimes with psychotic features on both ends of the spectrum. During these major depressive episodes, individuals may experience deep hopelessness, guilt, or worthlessness. When psychosis enters the picture, these feelings can evolve into delusions of persecution or hallucinations that reinforce negative thoughts. For instance, a person might believe that they are responsible for a catastrophic event or that voices are urging them to commit harmful acts. They may see or hear traumatic memories play in front of them, sending them into a state of fear and panic as if they were experiencing the event all over again.  The severity of these mood swings and their psychotic features can make bipolar disorder particularly unpredictable and dangerous. It’s not just about moving from mania to depression; it’s about dealing with the potential of losing touch with reality during both phases, a fact that makes this condition much more than a simple mood disorder. Guardrails to Protect Against Psychosis For those living with bipolar disorder, especially when psychosis is part of the equation, effective management is key. Medication, including mood stabilizers and antipsychotics, plays a central role in conventional psychiatric care. Psychotherapy, too, can help individuals recognize triggers and develop coping strategies for dealing with episodes of mania, depression, and psychosis. At BP Harmony, we advise people in the psychotic individual’s life (ie their community) to find a person whose opinion the individual respects and to consider the following steps:  This person must listen to the psychotic individual and identify those aspects of the person’s thinking that reflect a disconnect with reality.  Then ask if the person has always had these thoughts or if they are recent. If they are recent, then consider emphasizing that they didn’t see things their current way before. This will identify that there is some change in the person that others are noticing.  Express concern for the individual and invite them to consider the changes in their life due to the state they are in.  Reassure that you will be there to figure things out with them as opposed to suggesting that they need help. This may turn them away and cause them to reject help. The tricky challenge is to somehow get the person who is deeply caught in a false reality to realize on their own they have lost connection with reality. This is where a trusted person, psychiatrist, and therapist can effectively work together. In the meantime, the safest route is to get the person under the right medication or even admit them to a hospital to prevent harm to themselves and others.  Conclusion The connection between bipolar disorder and psychosis

bipolar vs unipolar depression
Understanding Bipolar Disorder

The Difference Between Bipolar Disorder and Unipolar Depression

The Difference Between Bipolar Disorder and Unipolar Depression Bipolar disorder and unipolar depression share many similarities, but they are fundamentally different in how they affect mood, the approach to treatment, and the role lifestyle plays in managing symptoms. Understanding these differences clarifies and helps people seek the right support. Let’s explore how these two conditions diverge in symptoms, treatment, and the potential for healing through lifestyle changes. Symptoms: Distinguishing the Two Conditions Bipolar and unipolar depression affect mood similarly in some ways and differently in key areas. Recognizing these distinct symptoms can lead to quicker, more accurate diagnoses and effective treatment. As we have discussed in previous posts, bipolar disorder presents itself as extreme fluctuations between emotional highs (mania or hypomania) and lows (depression), varying in frequency and intensity. These mood swings make it far more complex than unipolar depression though we are not discounting the severity and life-threatening nature of depression.  Unipolar Depression, on the other hand, is defined solely by persistent depressive symptoms. Unlike bipolar disorder, it does not involve manic or hypomanic episodes. Depressive episodes in unipolar depression are characterized by deep feelings of sadness, hopelessness, and a lack of energy. Physical symptoms like sleep and appetite changes often accompany these emotional lows. Another common characteristic is anhedonia, or the inability to experience pleasure. Those with unipolar depression may struggle to find joy in activities they once enjoyed, often feeling trapped in a low mood for extended periods like weeks, months, or even years. Treatment: Tailored Approaches for Bipolar And Unipolar Depression The difference between bipolar and unipolar disorder lies in the treatment path too. The focus for bipolar disorder is on stabilizing mood between two extremes, while treatment for unipolar depression centers on lifting the persistent feelings of sadness. Bipolar disorder requires a careful balancing act to manage both mania and depression. You can learn more about various treatment strategies in a previous post, but it is always recommended to work with a licensed health professional to get specific treatment advice. The general medication categories for bipolar disorder are mood stabilizers, antipsychotics, and sometimes antidepressants because of the risk of triggering hypomania or mania.  Unipolar Depression treatment focuses on alleviating depressive symptoms only. The absence of manic episodes means fewer variables to manage that are no less severe and challenging.Antidepressants are commonly prescribed to regulate mood by balancing neurotransmitters in the brain, lifting the cloud of depression. The Power of Lifestyle Changes A common thread and place for communal collaboration between the two patient communities is lifestyle. Lifestyle changes can have a profound impact on both bipolar disorder and unipolar depression. While these conditions may not be “curable,” individuals can achieve a “reversal” to the extent that the symptoms no longer exist.  In summary, bipolar disorder involves the complex interplay between mania and depression, requiring careful monitoring and stabilization. Unipolar depression focuses on lifting individuals from a persistent low mood. At BP Harmony, we have worked with Unipolar Depression clients by modifying the Five Pillars of Bipolar Disorder Recovery model: Sleep, Nutrition, Movement, Mindfulness, and Community. These five pillars are a recipe for good health for anyone, but when catered specially for people dealing with the extreme states of bipolar and unipolar depression, it can offer a significant decrease in suffering and the possibility of living full lives again.

bipolar disorder and spirituality
Understanding Bipolar Disorder

The Link Between Bipolar Disorder and Spirituality

The Link Between Bipolar Disorder and Spirituality Bipolar disorder (BPD) often feels like a force that pulls life apart. Yet, for those who face this challenge, there’s a possibility for deeper meaning and growth hidden within its chaos. Spirituality—whether through religious faith or personal practice—can offer not only solace but also a framework for understanding this unique experience. It is through this lens that many find hope and insight, transforming what is often viewed as suffering into a transformative journey. Spirituality: A Shelter Amidst the Storm Spirituality is more than just a set of beliefs or practices—it can be the ground beneath your feet when the world feels unsteady. Mental illness, particularly bipolar disorder, presents many trials, and spirituality can infuse these challenges with meaning.  This author was raised as a Muslim. It meant that connection to God became a source of strength, providing refuge through daily prayers and rituals and a sense that a Being, amidst the emotional turmoil, was listening with love and attention. Whether one believes in God as an external force or as an inner guide, faith can be an anchor. Even spiritual paths like Buddhism, which don’t center on a deity, offer deep practices of mindfulness and reflection.  The spiritual road begins by asking critical questions: Why is this happening? What does this moment seek to teach me? In facing mental illness, these questions can illuminate a path forward. The purpose of this struggle may not be immediately clear, but through reflection, it often becomes possible to transform pain into understanding. Trial as Purification Life’s trials have a way of shaping us, and few trials are as intense as navigating bipolar disorder. However, in many spiritual traditions, there’s a belief that trials are not random—they serve as opportunities for purification. In Islam, for example, hardship is seen as a test of character, a way to cleanse the soul and reconsider one’s choices. It’s a process of refinement, much like gold being purified by fire. The suffering brought on by bipolar disorder can be viewed through this lens—as a refining fire that burns away what no longer serves us. When health falters, it forces us to reevaluate the mundane and appreciate moments of peace we might otherwise take for granted. Spirituality reminds us that this world, with all its suffering and joys, is temporary. Both the highs and the lows are fleeting, but the lessons learned from them are enduring. When one reflects on their journey, there is an opportunity to see how the intense emotional pain can lead to a deeper appreciation—of life, of health, of simple pleasures. It is this perspective, gained through a spiritual framework, that transforms suffering into a process of refinement. Trial as Expansion Beyond purification, mental illness can also expand our capacity for empathy and compassion. When you’ve experienced the extreme emotions that come with bipolar disorder, you can’t help but feel a closer connection to the suffering of others. The moments of despair and elation widen the emotional bandwidth, creating space to understand the pain of those around us more profoundly. There is a TED Talk by Phil Borges that challenges listeners to think about mental illness differently. In his research, Borges spoke to shamans from different cultures—people who operate temporarily in heightened states of consciousness. What is striking is how many of these shamans first realized their calling through experiences we in the West would label as “mental illness.” These shamans, guided by elders, learned to ground their heightened awareness and use it in service to their communities. Borges asked a powerful question, “Are we, in the West, misdiagnosing people who are experiencing spiritual awakenings as mentally ill?” This reframing presents an empowering alternative to the narrative of bipolar disorder as an unchangeable affliction. What if, instead of merely managing symptoms, we could recognize the potential for awakening that this condition brings? The suffering that once seemed so isolating can become a bridge to something greater, a source of expanded understanding and awareness. The perspective shift from BPD as a disability to a potential awakening will take much advocacy, medical research, and courage. People like Phil Borges need the backing of BPD patients and medical experts to create research and writing to cause a shift in perspective. At BP Harmony, we believe that this diagnosis can be viewed the way Phil Borges presents.  Trial as Inspiration Mental illness has long been linked with creativity. Bipolar disorder, in particular, is known for inspiring great works of art, music, and literature. The emotional extremes of the condition allow those who live with it to access depths of feeling that others may not reach, and this wellspring of emotion often finds an outlet in creative expression. Vincent Van Gogh, for example, is one of the most famous artists whose work was deeply intertwined with his struggles with bipolar disorder. His paintings capture an intensity of emotion that resonates on a universal level. In the modern era, artists like Mariah Carey, Kanye West, and Demi Lovato have similarly channeled their own experiences of bipolar disorder into their art, offering the world a window into the depths of human experience. For this author, poetry became a lifeline during the healing journey. Writing helped make sense of the chaotic emotions. It became a way to transform the turmoil into something beautiful and meaningful. Through creativity, struggle was no longer just as a burden, but as a source of inspiration—a reminder that from suffering, something new and powerful can emerge. Conclusion Bipolar disorder is a profound and often difficult experience, but spirituality can offer a way to reframe it. Whether viewed as a path of purification, expansion, or inspiration, the link between bipolar disorder and spirituality is a powerful one. It allows us to find meaning where there might otherwise be only pain, and to see trials as opportunities for growth and transformation. When we engage with our mental illness from a spiritual perspective, we unlock the potential to transform suffering into something deeper—a

right medication for bipolar
Understanding Bipolar Disorder

Selecting the Right Medication for Bipolar Disorder

Selecting the Right Medication for Bipolar Disorder Managing bipolar disorder (BPD) is no easy journey and in many cases requires the use of pharmaceutical medication to minimize the intense symptoms and actions to protect the individual from harm to themselves and others. Because a person typically starts medication during an intense period of mania or depression, decisions are made quickly without properly understanding the benefits and potential risks of taking on medication. Typically, psychiatrists will prescribe bipolar disorder medication based on the symptoms presented, their medical training, and experience. There is a stage in the beginning where they will prescribe medication and observe how the patient reacts. If it works, then they will keep you on the medication and dosage. If it does not help the patient stabilize, then they will adjust the dosage or try a different drug or even drug type. This process of determining the right “cocktail” of drugs to stabilize the individual yields strong side effects and is designed to lessen or completely mute symptoms. They do not, however, cure the root cause, which is a combination of genetic components and external factors like stress, trauma, and lifestyle choices. In this post, we’ll explore the various classes of medications used to manage bipolar disorder, examples of commonly prescribed drugs, potential side effects, and the crucial role of lifestyle changes. When medications are combined with practices like sleep hygiene, movement, mindfulness, and community support, one begins the process of healing and potentially liberating oneself from medication partially if not completely. Types of Bipolar Disorder Medication Mood Stabilizers If you have bipolar disorder, mood stabilizers will likely be at the core of your medication treatment. These medications help to keep the extremes of mood in check, reducing both manic and depressive episodes by primarily affecting neurotransmitters and receptors. Let’s discuss some of the most commonly prescribed mood stabilizers in the US. Lithium: This is a strong medication for bipolar treatment, especially for mania. Lithium requires close monitoring by a psychiatrist because it can affect kidney and thyroid function. It is effective, yes, but it’s also a commitment. Side effects include weight gain, tremors, frequent urination, and long-term concerns with kidney function. Valproate (aka Depakote): Valproate is another go-to mood stabilizer, especially when lithium is not effective. It’s particularly effective in treating manic episodes. Side effects include weight gain, liver issues, drowsiness, and hair thinning. Regular liver function tests are necessary. While these medications can be lifesavers, they have strong side effects that can be unpleasant to bear. It’s important to openly communicate with your doctor about any side effects you experience so that adjustments can be made in a timely fashion. Anticonvulsants Anticonvulsants were originally developed to treat epilepsy but have proven effective in stabilizing mood, particularly for bipolar depression. Commonly prescribed medications for this class include: Lamotrigine (aka Lamictal): Particularly helpful in preventing depressive episodes, lamotrigine is favored by many because it has fewer side effects compared to other medications and is not as addictive as other medications listed on this blog. Side effects include poor concentration, weak memory, poor coordination, anxiety Carbamazepine (aka Tegretol): This anticonvulsant is primarily used to manage mania and is an option when other treatments fail. Side effects include dizziness, drowsiness, and potential impact on liver function. By now, it is apparent that these medications address mere symptoms and the side effects pose serious challenges for daily life. Presenting patients with only two options of uncontrolled mania/depression or being severely medicated is not a pleasant experience. We will get to a third more empowering option after discussing antipsychotics. Antipsychotics Antipsychotics are also commonly prescribed for acute manic or mixed episodes. From an experiential perspective, they slow down racing thoughts, facilitate falling asleep, and lower severe anxiety. They also serve as maintenance therapy, particularly if mood stabilizers alone aren’t enough. A few include Risperidone (aka Risperdal): this antipsychotic is prescribed particularly during manic or mixed episodes. It helps reduce symptoms like agitation, irritability, and rapid thoughts by balancing dopamine and serotonin levels in the brain. Common side effects include weight gain, sedation, constipation, and dizziness, while serious risks may include tardive dyskinesia and metabolic changes.  Olanzapine (aka Zyprexa): Often used during manic episodes, this medication is highly potent for sleep and is also notorious for significant weight gain and metabolic issues.Side effects include weight gain, increased blood sugar levels, and severe drowsiness. Quetiapine (aka Seroquel): This medication is increasingly popular and effective for both mania and depression. It is also a powerful sedative. Side effects also include weight gain and increased risk of metabolic syndrome. Aripiprazole (aka Abilify): This medication is known for having fewer side effects than other antipsychotics as it is a lighter option for mania or mixed episodes. Side effects include restlessness, weight gain, and sleep disturbances. Antidepressants Depressive episodes in bipolar disorder are tricky because they can tip the patient over to hypomania and even mania, especially if they are used without mood stabilizers. We publish a more nuanced conversation about BPD and antidepressants in future blog posts.  A Warning Before Starting Medication Every medication comes with unpleasant side effects, but what works wonders for one person might not for another. The journey toward finding the right medication will likely include some trial and error, which is also an unpleasant experience. But this experimentation process comes with two major risks: (1) these medications are habit forming and are difficult to abandon and (2) psychiatrists in the US are trained on which medications to prescribe based on a cluster of symptoms, but today (2024) they receive little to know training on how to safely get a patient off! There is little guidance on properly tapering off since going cold turkey runs a high risk of severe withdrawal symptoms and the relapsing into mania or depression. This is why it is vital to work with a healthcare provider who studies your health holistically. A good doctor will ask about lifestyle choices like diet, exercise, sleep, stress, and relationship quality before

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